Quantum yields of the photodissociation of HbO2 in the visible and near IR spectral region

The efficiency of the laser radiation effect on the oxyhemoglobin in blood vessels and its dependence on the wavelength of the irradiation are investigated. In vivo experimental measurements of the quantum yield of the laser-induced photodissociation of oxyhemoglobin in cutaneous blood vessels in the visible spectral range are presented. The spectral effectiveness of the photodissociation approximately correlates with their absorption spectrum and the transmission spectrum of skin tissue. Different aspects of biomedical application of this phenomenon are discussed. Non-invasive three-wavelength technique for determination of oxyhemoglobin concentrations in blood is also developed.