A negative search for four infectious agents in inflammatory bowel disease.

Diseased resected portions of intestine from patients with inflammatory bowel disease were examined by chicken embryo inoculation for the presence of chlamydia and histologically for the presence of chlamydia, intracellular campylobacters, Tyzzer's bacilli, and cryptosporidia. Chlamydia were not isolated from any of the seven colon specimens tested and chlamydia, intracellular campylobacters, Tyzzer's bacilli, and cryptosporidia were not demonstrated in 39 sections of colon and ileum from 16 IBD patients.