Effect of Hypophysectomy on Size of‘Remaining Kidney after Ureteroduo-denostomy and Contralateral Nephrectomy:

SummaryHypophysectomy was performed on adult male and female dogs by using the buccal approach. The left kidney which was removed through a midline abdominal incision served as a control, and the ureter of the right kidney was transplanted to the duodenum. The remaining kidney was removed 3 to 14 days later, and its weight and cytologic structure were compared with those of the control kidney.The remaining kidneys of the nonhypophy-sectomized dogs weighed an average of 106% more than the control kidneys. This is in contrast‘to a 25.15% average increase in the weight of the remaining kidneys over the control kidneys of the hypophysectomized dogs.Our thanks are due to Dr. Peter B. Dews for his help in analyzing the data statistically. We also wish to thank Mr. W. A. Meeker and Mr. Walter Ogg for their technical assistance.