Traffic-related air pollution as a risk factor for the development of childhood allergic diseases: the “Traffic, Asthma and Genetics” project

Background Inter-individual variability in associations between traffic-related air pollution and childhood allergic diseases may be explained by genetics and unexplored gene-environment interactions. We combined previously collected data from two Canadian (CAPPS, SAGE) and four European (BAMSE, PIAMA, GINI, LISA) birth cohorts to examine whether exposure to traffic-related air pollution interacts with a child’s genetic profile to impact the risk of developing childhood asthma, allergic rhinitis …