Rescue therapy combining intermediate-dose cytarabine with amsacrine and etoposide in relapsed adult acute lymphoblastic leukemia

2004 
A process for extracting extractable material from a base material in which it is present, while protecting against explosion of any solvent vapor in air includes heating by microwave radiation in a closed pressure-resistant and heat-resistant container, such base material, extractable material and organic extraction solvent, passing air near or into contact with the extraction container so that it will carry away from the container any escaping solvent vapor, and passing said air with the solvent vapor, if present, into contact with solvent detector which turns off a source of microwave radiation when the solvent vapor is present. Preferably the invented process will include passing the air, with any solvent vapor which may be present in it, to a flow detector, which will turn off the source of microwave radiation if flow ceases. The described processes may also include providing a rupture diaphragm to release extraction container contents at a pressure lower than that at which the container will fail, venting any contents exiting the container on to a collection container and venting vapor contents thereof to a solvent vapor detector. Also described are apparatuses for practicing the mentioned processes.
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