The relationship between inflammation and mean platelet volume in varicocele pathophysiology

Abstract Introduction The mean platelet volume (MPV) is an extensively employed laboratory indicator related to platelet volume and function in inflammatory circumstances. The aim of this study was to assess the relationship between inflammation and mean platelet volume in varicocele pathophysiology. Methods We conducted a recent study, which included 131 varicocele subjects and 82 healthy controls. The identification of varicocele was based on the results from both physical examination and color Doppler ultrasound. We analyzed some laboratory markers including haemogram tests in two groups. Results There were no significant differences in the two groups in terms of baseline characteristics. MPV values were statistically higher in the varicocele group (9.73 ± 0.86 fL) than in the control group (9.03 ± 0.70 fL) ( p p Conclusion MPV can offer information on varicocele pathophysiology. Increased MPV levels in varicocele patients may be associated with inflammation.