Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone

Yigang Tong,Weifeng Shi,Di Liu,Jun Qian,Long Liang,Xiao-Chen Bo,Jun Liu,Hong Guang Ren,Hang Fan,Ming Ni,Yang Sun,Yuan Jin,Yue Teng,Zhen Li,David Kargbo,Foday Dafae,Alex Kanu,Cheng-Chao Chen,Zhi-Heng Lan,Hui Jiang,Yang Luo,Hui-Jun Lu,Xiao Guang Zhang,Fan Yang,Yi Hu,Yuxi Cao,Yong qiang Deng,Haoxiang Su,Yu Sun,Wen-Sen Liu,Zhuang Wang,Cheng-Yu Wang,Zhao-Yang Bu,Zhen-Dong Guo,Liu-Bo Zhang,Wei-Min Nie,Changqing Bai,Chun-Hua Sun,Xiaoping An,Pei-Song Xu,Xianglilan Zhang,Yong Huang,Zhiqiang Mi,Dong Yu,Hong Wu Yao,Yong Feng,Zhiping Xia,Xuexing Zheng,SongTao Yang,Bing Lu,Jia Fu Jiang,Brima Kargbo,Fu-Chu He,George F. Gao,Wu-chun Cao

Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone

2015

The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous outbreaks and that the genetic diversity of the virus has increased substantially, with the emergence of several novel lineages.

Keywords:

Ebola virus
Viral evolution
Virology
Genome
Evolutionary dynamics
Virus
Genetic diversity
Outbreak
Biology
Molecular epidemiology
sierra leone
Ebolavirus

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