Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes: Mendelian Randomization and Observational Analyses.

Jakie Guertin,Yannick Kaiser,Hasanga D. Manikpurage,Nicolas Perrot,Raphaëlle Bourgeois,Christian Couture,Nicholas J. Wareham,Yohan Bossé,Philippe Pibarot,Erik S.G. Stroes,Patrick Mathieu,Marie-Annick Clavel,Sébastien Thériault,S. Matthijs Boekholdt,Benoit J. Arsenault

Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes: Mendelian Randomization and Observational Analyses.

2021

Jakie Guertin
Yannick Kaiser
Hasanga D. Manikpurage
Nicolas Perrot
Raphaëlle Bourgeois
Christian Couture
Nicholas J. Wareham
Yohan Bossé
Philippe Pibarot
Erik S.G. Stroes
Patrick Mathieu
Marie-Annick Clavel
Sébastien Thériault
S. Matthijs Boekholdt
Benoit J. Arsenault

Background: Elevated Lp(a) (Lipoprotein(a)) levels are associated with coronary artery disease (CAD), ischemic stroke (IS), and calcific aortic valve stenosis (CAVS). Studies investigating the asso...

Keywords:

Lipoprotein
Mendelian randomization
Aortic valve stenosis
Genotype
Calcific aortic valve stenosis
Cardiology
Medicine
Internal medicine
Stroke
Gene expression
Coronary artery disease

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