The morphofunctional state of the supraopticoneurohypophyseal system of rats in hypoparathyroidism

1. An increase in the functional activity of the SON of the hypothalamus and a decrease in the amount of neurosecretum in the posterior lobe of the hypophysis on the 5th day of parathyroprivic hypocalcemia attest to an intensification of discharge of neurosecretum into the blood stream. 2. The decrease in the functional activity of the neurosecretory cells of the SON with the simultaneous increase in the amount of neurosecretum in the posterior lobe of the hypophysis on the 15th and 30th days of development of parathyroprivic hypocalcemia attest to a delay in the discharge of neurosecretum. 3. Features appear on the 60th day of parathyroprivic hypocalcemia in the neurosecretory cells of the SON which point to the restoration of neurosecretion, but the amount of neurosecretum in the posterior lobe of the hypophysis is still significantly higher than in the control, i.e., the process of release of neurosecretum has not been restored.