Microbiologic diagnosis of mixed anaerobic and aerobic surgical infections

: One hundred and twelve patients with purulent affections of the abdominal and thoracic cavities as well as soft tissues and 49 patients with suspected generalization of the infection were examined. It was shown that the position of mixed anaerobic and aerobic infections in various groups of the patients could reach 70-80 per cent while the species composition of the pathogens was close to that of the normal microflora in the affected organ or its region. Bacteroides spp. played the main role in the development of anaerobic sepsis and conditioned a distinctive process. There was observed synergism of Escherichia coli and Staphylococcus spp. and they were shown to serve as indicators of the anaerobic infection due to these species in definite biotops. The use of GLC markedly lowered the time required for diagnosis of anaerobic infections which provided rational chemotherapy at the early stages of the disease with an account of the data on monitoring of the suppuration causative agent.