Изменения воздухонаполненности легких у больных бронхиальной астмой в зависимости от степени контроля над заболеванием

2014 
The aim of the work was to estimate the disorders in lungs inflation in patients with bronchial asthma depending on the degree of control over the disease. The authors had a complex study of patients with bronchial asthma with controlled and uncontrolled course that included spirography (including the one with cold air test and bronchodilation test), bodypletismography and computer-aided tomography with zone densitometry and 3D volumetry. The results showed the reliable change in the parameters depending on the degree of the control over the disease, they were the worst in the group of patients with uncontrolled course of asthma. The patients who lost control over the disease had the increase of the degree of pulmonary ventilation maldistribution and these changes were focused in the low parts of the lungs. Using complex diagnostic possibilities, the authors did discriminant analysis, whose results allow to identify the loss of asthma control, contributing to the timely correction of the therapy.
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