Влияние экспериментального ожирения на состояние периферического кровообращения в различных тканях по данным оксиметрии
2015
The peripheral circulation of blood was estimated in various tissues affected by the modeling of alimentary obesity in the experiment on 10 mongrel dogs. The modeling of the obesity was performed according to the original procedure involving the use of high calory diet with the predominance of fats, and the administration of insulin for appetite stimulation in combination with physical inactivity, that ensured the weight gain of an animal during 1 month by 20-25% from the baseline value registered before the modeling of obesity. The criterion for the assessment of the state of peripheral circulation of blood was the dynamics of indicators of oximetry in various tissues as compared with the original, registered before the modeling of obesity. It was found out that there was a general trend of the reduction of indicators of oximetry in all tissues under the research with the development of obesity. It is advisable to continue the study with the regard to the structure of tissues in order to evaluate the clinical significance of impaired peripheral circulation of blood under the development of obesity.
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