The Properties of HPMC:PEO Extended Release Hydrophilic Matrices and their Response to Ionic Environments.

Anran Hu,Chen Chen,Michael D. Mantle,Bettina Wolf,Lynn F. Gladden,Ali R. Rajabi-Siahboomi,Shahrzad Missaghi,Laura M. Mason,Colin D. Melia

The Properties of HPMC:PEO Extended Release Hydrophilic Matrices and their Response to Ionic Environments.

2017

Anran Hu
Chen Chen
Michael D. Mantle
Bettina Wolf
Lynn F. Gladden
Ali R. Rajabi-Siahboomi
Shahrzad Missaghi
Laura M. Mason
Colin D. Melia

Purpose Investigate the extended release behaviour of compacts containing mixtures of hydrophilic HPMC and PEO in hydrating media of differing ionic strengths.

Keywords:

Ionic bonding
Dissolution
Matrix (mathematics)
Chemistry
Chromatography
hydrophilic matrix
Chemical engineering
extended release
Analytical chemistry
pharmacology toxicology

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