A Genomic Profile of Local Immunity in the Melanoma Microenvironment Following Treatment with α Particle-Emitting Ultrasmall Silica Nanoparticles

Aleksandra M. Urbanska,Raya Khanin,Simone Alidori,Sam Wong,Barbara P. Mello,Bryan Aristega Almeida,Feng Chen,Kai Ma,Melik Z. Turker,Tatyana Korontsvit,David A. Scheinberg,Pat Zanzonico,Ulrich Wiesner,Michelle S. Bradbury,Thomas P. Quinn,Michael R. McDevitt

A Genomic Profile of Local Immunity in the Melanoma Microenvironment Following Treatment with α Particle-Emitting Ultrasmall Silica Nanoparticles

2020

Aleksandra M. Urbanska
Raya Khanin
Simone Alidori
Sam Wong
Barbara P. Mello
Bryan Aristega Almeida
Feng Chen
Kai Ma
Melik Z. Turker
Tatyana Korontsvit
David A. Scheinberg
Pat Zanzonico
Ulrich Wiesner
Michelle S. Bradbury
Thomas P. Quinn
Michael R. McDevitt

An α particle-emitting nanodrug that is a potent and specific antitumor agent and also prompts significant remodeling of local immunity in the tumor microenvironment (TME) has been developed and ma...

Keywords:

Melanoma
Tumor microenvironment
Immunity
T cell
silica nanoparticles
Natural killer cell
Medicine
Cancer research
Molecular biology
Genomic Profile
Immunotherapy
α particles
local immunity

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations