Inhibition of integrinv?6, an activator of latent TGF?, prevents radiation-induced lung fibrosis

An underwater apparatus for transmitting and receiving high rate data and voice communication including a transmitter, a receiver, and a Doppler frequency shift compensator. The transmitter includes a data source comprising digital data to be transmitted by the apparatus through the water, a serial-to-parallel data processor for splitting the serial digital data into n parallel data channels, a n-channel modulator for receiving the n parallel data channels and for modulating those channels with n pairs of ultrasonic carriers to produce a modulated signal. The transmitter also includes a hydrophone for receiving and transmitting the modulated signal. The receiver includes a hydrophone for receiving a modulated signal. The receiver also includes RF circuitry for amplifying and shaping the received modulated signal, a serial-to-parallel data processor for splitting the amplified and shaped data into n parallel channels, a n-channel demodulator for demodulating the shaped signal and for outputting n channels of digital data, and a parallel-to-serial data processor for receiving n parallel channels of data from the demodulator and for combining those channels into serial data. The Doppler compensator measures the frequency of at least one of two unmodulated signals transmitted as part of the modulated signal and compares the measured frequency with a predetermined frequency. Operation of the demodulator is adjusted to compensate for any deviation between the measured and predetermined frequency.