Method and system for inspection implementation

A method of operating a screening system includes applying an electromagnetic field to a subject in a region at least partially enclosed by electromagnetic shielding, and measuring an output from a sensor. The output is representative of an interaction of the electromagnetic field and the subject. A trace vapor is collected from the subject within the region, and the trace vapor is identified. Based on the measured sensor output and the identified trace vapor, whether a target material is associated with the subject is determined.