Antigenic determinants of normal serum proteins bound to the surface antigen structures of the serum hepatitis B virus (HBsAg)

: The coprecipitation test under conditions of rocket immunoelectrophoresis was used for the analysis of human normal serum antigens associated with HBsAg structures. Antigenic determinants of human serum albumin were detected in the HBsAg composition. In the multicomponent test system, 125I-HBsAg coprecipitated with some more distinct antigenic systems in addition to albumin. Possible mechanisms of formation of classes of HBsAg structures differing in host antigens are discussed.