Method of finding an active ingredient, which allows killing of tumor cells in a tumor disease of a mammal or human

2005 
Method of finding an active ingredient, which allows killing of tumor cells by inducing apoptosis by means of an effector in a tumor disease of a mammal or human, comprising the steps of: a1) providing a plurality of test mixtures by seeding of tumor cells in a respective culture vessel with cell culture medium, wherein the tumor cells or additionally seeded effector cells which release potentially apoptosis inducing cellular effectors, are each seeded in a cell density that is suitable for the on addition of a on the exterior to cause tumor cells acting Katalaseinhibitors and incubation of the test batches with the cultivation of the tumor cells or the tumor cells and effector cells suitable conditions to apoptosis of tumor cells, b1) adding at least one each of a candidate drug to each one of the experimental batches, wherein at least one test mixture is left to which no potential drug is added, c1) incubation of the test batches for the cultivation under suitable conditions of tumor cells and d1) determining the experimental approach / of the experimental batches, in which / whom the percentage of apoptotic tumor cells ...
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