Active suppression prevents the return of threat memory in humans.

Unbidden distressing memories inflict serious damage on mental health. Extant research highlights the importance of associative learning in modulating aversive memory. We report that conscious active suppression eliminates learned fear responses independent of memory triggers and is related to individual difference in thought control ability; in contrast, thought diversion only reduces cue-specific fear response. These results suggest potential avenues for treatment of persistent maladaptive memories by engaging declarative mnemonic control mechanisms. Ye Wang et al. show that conscious thought active suppression eliminates learned fear responses whereas thought diversion only reduces cue-specific fear response. This study suggests that declarative control mechanisms may be utilized to treat persistent maladaptive memories.