Antimicrobial Agents Use in 269 Patients with Bacterial Infective Diseases

OBJECTIVE To investigate the application of antimicrobial agents in hospital and the etiology detection status.METHODS The inpatients with bacterial infectives diseases in 2007-2009 years were reviewed with the prospective and retrospective study,and Excel software was used for data processing.RESULTS The majority was incision infection(34.94%),followed by upper respiratory tract infection(23.42%) from 269 cases of bacterial infections inpatients,the rate of etiology detection was 24.16%.The initial use of antimicrobial agents was empirically,especially the third and fourth generation cephalosporins were the highest(24.35%) and penicillins were the second(19.89%).The single-drug rate was 20.82%,the double-drug rate accounted for 64.31%,the triple-drug use was 14.87% and without more than triple-drug use.The major phenomena of irrational drug use were the drug dose,frequency,inappropriate combination therapy and the over short interval of drug replacement.CONCLUSIONS The most common bacterial infection in hospital is incision infection,the antimicrobial drug use is reasonable in general,but the rate of the etiology detection is low.The prescription of some clinicians is not standard,and the training needs to be strengthened.