Tandem Copper Catalyzed Regioselective N-Arylation-aza-Michael Addition: Synthesis of Tetracyclic 5H-Benzothiazolo[3,2-a]quinazoline Derivatives.

Jyoti M. Honnanayakanavar,Battu Harish,Jagadeesh Babu Nanubolu,Surisetti Suresh

Tandem Copper Catalyzed Regioselective N-Arylation-aza-Michael Addition: Synthesis of Tetracyclic 5H-Benzothiazolo[3,2-a]quinazoline Derivatives.

2020

Jyoti M. Honnanayakanavar
Battu Harish
Jagadeesh Babu Nanubolu
Surisetti Suresh

ABSTRACT: A copper catalyzed tandem process integrating regioselective N-arylation followed by aza-Michael addition is disclosed using 2-aminobenzothiazoles and ortho-halo cinnamic acid congeners. ...

Keywords:

Regioselectivity
Chemistry
Cascade reaction
copper catalyzed
Organic chemistry
quinazoline derivatives
Cinnamic acid
Michael reaction
Tandem

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