Genetics in Otolaryngology: Translational Research

Program Description: Recent years have seen great advances in our understanding of the molecular genetic basis of many clinical disorders. Building on the success of the Human Genome Project, new technologies are in development to identify disease-causing mutations through genetic testing. However, there is a knowledge gap among otolaryngologists regarding which patients should undergo genetics evaluation and how genetic testing should be utilized in the care of patients. The three participants are clinician-scientists who investigate the genetic factors underlying human disease, and also apply their understanding of genetics to the care of patients. This panel will discuss the state of the art in genetic testing in otolaryngology as well as translation of recent research which will soon be clinically available. Dr Gruber will address cancer genetics, applying his work in cancer in general to head and neck tumors; Dr Runge will discuss the evaluation of auditory neuropathy beyond routine clinical measures...