Therapeutic Management of Demineralized Dentin SurfacesUsing a Mineralizing Adhesive To Seal and Mineralize Dentin, DentinalTubules, and Odontoblast Processes

Dentin hypersensitivity is attributable to the exposed dentin and its patent tubules. We proposed the therapeutic management of demineralized dentin surfaces using a mineralizing adhesive to seal and remineralize dentin, dentinal tubules and odontoblast processes. An experimental self-etch adhesive and a mineralizing adhesive consisting of the self-etch adhesive and 20 wt% of poly-aspartic acid-stabilized amorphous calcium phosphate (PAsp-ACP) nanoparticles were prepared, which were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and scanning electron microscopy (SEM). After 60 acid-etched mid-coronal dentin discs were treated with distilled water (control), a desensitizing agent (Gluma), the experimental self-etch adhesive and the mineralizing adhesive, dentin permeability was measured and their mineralization was evaluated by Raman, FTIR, XRD, TEM, and selected area electron diffraction (SAED), irrespective of abrasive and ...