A case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
2020
We encountered a 12-year-old boy with type 2 diabetes who was born small-for-gestational age (SGA). We described his clinical characteristics and a possible etiological factor for development of hyperglycemia. He developed well with sufficient nutrition and progressed to being overweight at 6 years of age due to a high-calorie high-protein intake diet. He showed a diabetic pattern with a normal insulin response on an oral glucose tolerance test conducted with the urine glucose screening program at schools. He exhibited a large total fat area of 239.4 cm(2) ; particularly, his visceral fat area (VFA) was 103.0 cm(2) with a high ratio of VFA to subcutaneous fat area (0.76). The present case might show that insulin resistance, possibly due to accumulation of a great amount of VF, might be attributed to the pathogenesis of type 2 diabetes in the children born SGA.
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