Role of Cu2+ in free radical oxidation of human serum albumin and L-tyrosine dipeptide with multicomponent metal-containing xenobiotic.

Cu2+ entering the composition of multicomponent metal-containing xenobiotic in vitro initiated free radical oxidation of human serum albumin and L-tyrosine dipeptide. Oxidative modification was accompanied by the formation of derivatives of amino acids tyrosine and tryptophan and structural changes in human serum albumin.