Clinical Applications of Induced Pluripotent Stem Cells in Cancer

Several approaches have been used to understand cancer pathogenesis. The discovery of the human induced pluripotent stem cells (hiPSCs) opens a new perspective to study different diseases, including cancer. These cells have two important properties, which are the self-renewal capacity and the ability to differentiate into any cell type of the human body. Basic research in the hiPSCs field has made progress in the application of new strategies with the aim to enable an efficient production of high quality of hiPSCs for safety and efficacy, necessary to future applications for clinical practice. In this chapter, we show the recent advances in hiPSCs’ basic research and some potential clinical applications in cancer. We also present the importance in using statistical methods to evaluate the possible validation of hiPSCs for therapeutic use.