β-Klotho deficiency shifts the gut-liver bile acid axis and induces hepatic alterations in mice
2018
β-Klotho (encoded by Klb) is an obligate coreceptor, mediating both fibroblast growth factor (FGF)15 and FGF21 signaling. Klb−/− mice are refractory to metabolic FGF15 and FGF21 action and exhibit ...
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