Thiosemicarbazonate complexes with affinity for amyloid-β fibers: synthesis, characterization and biological studies

Arantxa Pino-Cuevas,Paula D. Raposinho,Célia Fernandes,António Paulo,Ulrich Abram,Rosa Carballo,Ezequiel M. Vázquez López

Thiosemicarbazonate complexes with affinity for amyloid-β fibers: synthesis, characterization and biological studies

2019

Arantxa Pino-Cuevas
Paula D. Raposinho
Célia Fernandes
António Paulo
Ulrich Abram
Rosa Carballo
Ezequiel M. Vázquez López

Aim: Obtain radioimages of amyloid-β fibers using 99mTc-complexes. Methodology: Tridentate thiosemicarbazone and thiocarbonohydrazone ligands containing fragments (stilbene, azobenzene, benzothiazo...

Keywords:

Combinatorial chemistry
Biochemistry
Semicarbazone
Biology
Azobenzene
Rhenium
Amyloid
Ligand
Stereochemistry
amyloid β
biological studies

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