Deep Reinforcement Learning Designed Shinnar-Le Roux RF Pulse using Root-Flipping: DeepRFSLR.

novel approach of applying deep reinforcement learning to an RF pulse design is introduced. This method, which is referred to as DeepRFSLR, is designed to minimize the peak amplitude or, equivalently, minimize the pulse duration of a multiband refocusing pulse generated by the Shinar Le-Roux (SLR) algorithm. In the method, the root pattern of SLR polynomial, which determines the RF pulse shape, is optimized by iterative applications of deep reinforcement learning and greedy tree search. When tested for the designs of the multiband pulses with three and seven slices, DeepRFSLR demonstrated improved performance compared to conventional methods, generating shorter duration RF pulses in shorter computational time. In the experiments, the RF pulse from DeepRFSLR produced a slice profile similar to the minimum-phase SLR RF pulse and the profiles matched to that of the computer simulation. Our approach suggests a new way of designing an RF by applying a machine learning algorithm, demonstrating a “machine-designed” MRI sequence.