Attempted application of bioengineered/biosynthetic supporting matrices with phosphatidylinositol-trisphosphate-enhancing substances to organ culture of human primordial follicles

Galit Lerer-Serfaty and Dr. Nivin Samara contributed equally to this study as first authors. Capsule PEG-fibrinogen hydrogels seem to have an advantage over alginate scaffolds for culturing human primordial follicles. Folliculogenesis is not enhanced with the addition of PIP3-inducing substances or use of thin-slice sectioning.