Rare sulfated purine alkaloid glycosides from Bruchidius dorsalis pupal case

Abstract Three new sulfated isoguanine alkaloid glycosides, locustoside A disulfate (1), saikachinoside B disulfate (2), and saikachinoside A trisulfate (3), have been isolated from the pupal case of the wild bruchid seed beetle Bruchidius dorsalis (Chrysomelidae, Bruchinae) infesting the seed of Gleditsia japonica Miquel (Fabaceae) along with the known compounds 9–11. The structures of the new compounds were determined through spectroscopic data and X-ray crystallographic analysis. The isolated compounds were evaluated for their inhibitory activity against starfish embryogenesis.