Creatinine Clearance: An Inadequate Marker of Renal Filtration in Patients with Early Posthepatitic Cirrhosis (Child A) without Fluid Retention and Muscle Wasting

Glomerular filtration rate (GFR) was measured in 19 patients with Child A liver cirrhosis by comparing the endogenous creatinine clearance with inulin clearance. Inulin clearance averaged 90 ± 4.4 ml/min × 1.73 m2, while creatinine clearance averaged 122 ± 7 ml/min × 1.73 m2 (p