A single scan technique for estimating acid output

Abstract A single scan technique using 99m Tc has been developed for the measurement of gastric acid output. After an overnight fast, pentagastrin (6 μg/kg S.C.) was given 15 min before 99m Tc (1 mCi i.v.), and a scan of the abdomen was performed 15 min later using a double-headed scanner. Accumulation of isotope within the stomach was then calculated from the scan and expressed as a percentage of the injected dose. Pentagastrin-stimulated intragastric activity correlated with acid output measured conventionally on a separate occasion (r = 0.87, P