Assessment of the antimicrobial potential of Dalbergia sisso against eight pathogenic bacteria - an in vitro study

ABSTRACT In this study, Dalbergia sisso (Family: Fabaceae), was evaluated for its antibacterial potential against eight human pathogenic bacterial strains. Triple maceration method was adopted for the methanolic extraction of whole plant (pods, leaves, stem bark, root bark) and leaves. In-vitro, antimicrobial test was performed by disc diffusion method in order to analyze the percentage zone of inhibition. Whole plant’s extract showed good antibacterial activity against S. aureus (18.00), S. pneumoniae (17.50), B. cereus (17.90), B. pumilus (16.45), E. coli (19.00), K. pneumoniae (17.45), P. aeruginosa (16.20) and C. freundii (15.00), with relative percentages of inhibition 81.00, 80.54, 76.65, 64.65, 78.45, 72.45, 70.37 and 62.30 respectively, as compared with leaves with relative percentages of inhibition 70.56, 67.32, 54.20, 43.24, 62.80, 57.03, 51.05 and 36.65 against same microbes. Modified agar well diffusion method was used to measure the minimum inhibitory concentration (MIC) and MIC values of the whole