Dynamics of the epidemic process and the course of the COVID-19 in pregnant women of the Far Eastern and Siberian Federal Districts

Aim To evaluate an epidemiological characteristic and the course of COVID-19 in pregnant women from the Far East and Siberian Federal Districts of Russia Materials and methods The analysis of operational information on the incidence of COVID-19 and the its features in pregnant women and alter childbirth prov ided by the chief obstctrician-gynecologists of the Far F astcrn Federal District and Siberian Federal District on Ma)-25, 2020 and August 25,2020 is carried out Mathematical analysis included descriptive statistics methods, analy sis of contingency tables, where the x2 value, the achieved significance level (p) Results On August 25, 2020, 2010 cases of COVID-19 in pregnant women were detected in two subjects, including 134 active cases In the population, the proportion of pregnant women among cases of COVID-19 was 1 45% Pneumonia in pregnant women was registered in 44 8% of cases, severe course of the disease-in 37%, hospitalization in RAW-in 1 9% of cases, mechanical ventilation-0 In the population, pneumonia was registered in 24 4% of cases, hospitalized in RAW-2 1%, on mechanical ventilation-0 77% The incidence in pregnant women was 1464 7 per 100 000 (in the population-591-8 per 100 000) 23 (1 76%) COV1D-19 (+) newborns were identified, despite preventive measures and separation of mother and child immediately after childbirth, which docs not exclude vertical transmission of the disease Maternal mortality was 2 (0 1%) cases vs population mortality 1 49% Perinatal mortality was 7 (0 35%) cases There were 5 (0 25;) stillbirths Farly neonatal mortality was 2 (0 1%) cases Conclusions The incidence of COVID-19 in pregnant women in the Far East and Siberia is higher than in the general population with a higher incidence of pneumonia, but a milder course: Less need lor 1CU, mechanical ventilation and mortality 23 cases of SARS-CoV-2-positivc newborns, despite the separation of mother and child, do not exclude the possibility of vertical transmission of infection © 2021 Universidade de Sao Paulo All rights reserved