Targeted dry skin treatment using a multifunctional moisturizer

The article of Stettler et al. [1] points out dry skin is still a major problem globally and as a result, truly multifunctional moisturizers, with ingredients that have multiple mechanisms of action, need to be developed to address the underlying changes in the (patho)physiology of the condition. This was the focus of Stettler et al. 'Targeted dry skin treatment using a multifunctional moisturizer'. As a result, it is important to address the claimed product efficacy as a multifunctional moisturizer relative to those reported by others, especially to the claim of improving 'overall epidermal differentiation' from use of the formulation.