Microwave-assisted synthesis of asymmetric thiocarbonohydrazones under solvent-free conditions

Abstract Six new asymmetric thiocarbonohydrazones 3a – 3f were synthesized from following steps: firstly hydrazine hydrate reacted with carbon disulfide to form thiocarbonohydrazide ( 1 ) under microwave irradiation. Then compound ( 1 ) reacted with ketone and different aldehydes step by step to give 3a – 3f with excellent yields under solvent-free conditions using microwave irradiation. Their structures have been determined by elemental analysis, IR, MS and 1 H NMR data.