Spectrophotometric estimation of Primaquine

The present paper deals with the development of a simple, rapid and sensitive spectrophotometric method for the estimation of primaquine phosphate chemically [ 8-amino (4- amino-1-methylbutyl) -6-methoxyquinoline phosphate is an antimalarial drug of usual dosage in an equivalent of 15mg ones a day. Primaquine Phosphate by reacting with sodium vanadate to give a pink colour and maximum colour intensity obtained by 0.3 ml perchloric acid. Which has an absorbance maximum at 560 nm.