Flail Mitral Valve Associated with Iliac Artery Aneurysm: Diagnostic Challenges of a Potential Syndromic Pattern. Case Report

Severe mitral valve regurgitation can be caused by a spectrum of disorders that can influence the management of this entity. Here we describe the diagnostic work-up in the case of a patient presenting with flail mitral valve secondary to Barlow’s disease and concomitant fever, underscoring the difficulty in providing differential diagnosis of the underlying causative etiology and to plan subsequent appropriate treatment. Diagnostic tests leaded to the incidental discovery of concomitant iliac artery aneurysm; hence, we discuss the association between Barlow’s disease and arterial abnormalities, possibly pointing towards a syndromic pattern related to common pathogenic background affecting connective tissue.