Research of early prenatal diagnosis to Hb Bart's hydrops fetus by ultrasonography

Objective To obtain the unharmful image method to prenatal diaglosis through the ultrasound examination of the fetus with high risk of Hb Bart's hydrops during 12~20 pregnancy weeks.Method Examine 320 cases with high-risk of Hb Bart's hydrops fetus by ultrasound and genetic analysis using gap-PCR technology,and compare with the information of the normal group at the 12~20 pregnancy weeks.Results 73 Hb Bart's hydrops fetuses diagnosed by genetic analysis had abnormal ultrasound images.58 cases were the enlarged cardiothoracic rate(0.30),18 cases were incrassated nuchal translucency,18 cases were echogenic bowel and 22 cases were ascites.The placenta thickness was not incrassated,but their average thickness was significantly higher than normal.Conclusions Ultrasonography is a safe,precise and effective method for the early prenatal diagnosis Hb Bart's hydrops fetus during 12~20 weeks.