Stereochemical analogs of a muscarinic, ganglionic stimulant. cis- and trans-4-[N-(3-Chlorophenyl)carbamoyloxy]-2-butenyltrimethylammonium iodides

Wendel L. Nelson,D. S. Freeman,P. D. Wilkinson,F. F. Vincenzi

Stereochemical analogs of a muscarinic, ganglionic stimulant. cis- and trans-4-[N-(3-Chlorophenyl)carbamoyloxy]-2-butenyltrimethylammonium iodides

1973

Wendel L. Nelson
D. S. Freeman
P. D. Wilkinson
F. F. Vincenzi

Aus dem 1-Chlor-butin-carbamidat (I) erhalt man mit Dimethylamin und nachfolgender Quaternierung sowie spezifischer selektiver Hydrierung uber vergiftetem Pd das cis-Olefin (II).

Keywords:

Cis–trans isomerism
Stereochemistry
Stimulant
Muscarinic acetylcholine receptor
Organic chemistry
Chemistry
Structure–activity relationship
Ganglionic Stimulants
electric stimulation

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