Haloacid Induced Alterations in Fertility and the Sperm Biomarker SP22 in the Rat Are Additive: Validation of an ELISA

*North Carolina State University, Department of Environmental and Molecular Toxicology, Raleigh, North Carolina 27606; and †United StatesEnvironmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory,Reproductive Toxicology Division, MD #72, Research Triangle Park, North Carolina 27711Received May 10, 2004; accepted July 1, 2004