Trends in incidence and outcomes of necrotizing enterocolitis over the last 12 years: a multicenter cohort analysis

Purpose: We sought to describe changes in incidence and mortality of necrotizing enterocolitis (NEC) for very low birthweight (VLBW) infants in the United States over the past 12-years. Associated changes in management strategies were also evaluated. Methods: Data were prospectively collected on VLBW infants (≤1500g) born 2006 to 2017 and admitted to 820 US Vermont Oxford Network member centers. NEC was defined by …