Sézary's syndrome: a clinical evaluation of eight patients

SUMMARY Clinical and laboratory investigations of 8 patients with Sezary's syndrome are presented. Sezary cells were found in peripheral blood as well as in bone marrow and lymph nodes. The overall follow-up period was 8 years. Different therapeutic regimens were given. The best results were obtained with chlorambucil and prednisone orally, combined with topical application of nitrogen mustard. Three patients died of pneumonia and septicaemia.