87 DNA markers for a paternity testing: Are they sufficient?

Abstract We report a judicial paternity testing with two exclusions at D2S1338 and vWA loci. Since these results suggested that the true father should be a close male relative of the tested man, mother was included into analysis. Subjects were also typed for 24 validated STRs, 11 STRs for linkage analysis, 8 X-STRs and 30 DIPs, for a total of 87 markers. No further exclusions were found. Paternity index, taking into account mutation rates for D2S1338 and vWA, was 1.45×10 13 ( W =0.99999999999993). The final odds that the true father should be the untyped brother of the alleged father, that refused DNA profiling, was 1:192.