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A method of reducing an amine

2014 
The present invention provides a method of producing a reference standard for the bambuterol, it belongs to the technical field of pharmaceuticals. Said method comprising: a raw material in the presence of an acid catalyst, into hydrogen reduction, to give the product, the acid is hydrochloric acid, phosphoric acid, phosphoric acid, acetic acid, formic acid, trifluoroacetic acid, benzenesulfonic acid, toluenesulfonic acid, malic acid and the like; the hydrogen pressure is not more than 180kPa.
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