Ungewöhnliche Metastasenlokalisation eines Nierenkarzinoms

BACKGROUND: An isolated intralaryngeal metastasis developed six years after removal of the right kidney because of hypernephroma. PATIENTS: We report this rare case of laryngeal metastasis of hypernephroma in a 42-year-old female. A round intralaryngeal tumor inserting at the anterior commissure was found and removed. RESULTS AND CONCLUSIONS: Knowledge of the history of the malignoma of the kidney led us to correct diagnosis. The clinical and histological findings are presented. Neoplasms of the kidney can metastasize years after removal of the primary tumor. The cause of this behavior of the tumor cells is still unknown. In patients with a history of hypernephroma, every polypus of the mucous membrane of the upper aerodigestive tract has to be considered suspect. Histological examination should always include immunohistological examination of the tissue. At least in the case of isolated laryngeal metastasis, a laryngectomy should be considered.