Method for separating refined dihydroartemisinic acid from artemisinin production waste through ion-exchange resin method

2014 
The invention discloses a method for separating refined dihydroartemisinic acid from artemisinin production waste through an ion-exchange resin method. The method for separating the refined dihydroartemisinic acid from the artemisinin production waste through the ion-exchange resin method comprises enabling the dried artemisinin production waste to be served as raw materials, dissolving through a sodium hydroxide solution, centrifuging to remove precipitate, obtaining supernatant liquor, gradually adding preprocessed and balanced processed anion exchange resin, flushing through deionized water, performing desorption, collecting eluent, perform vacuum concentration, performing extraction through organic solvent and finally obtaining high-purity dihydroartemisinic acid products through crystallization. According to the method for separating the refined dihydroartemisinic acid from the artemisinin production waste through the ion-exchange resin method, the artemisinin production waste is served as the raw materials firstly and the dihydroartemisinic acid is separated and purified through the ion-exchange resin method; the concentration time and energy consumption are reduced due to the vacuum concentration and organic solvent extraction combined technology, the product yield is increased, production costs are reduced, the product purity which is high is more than 99%; the recovery rate which is high in larger than 80%; the operation is convenient, the production is large, and industrial scale production is easy to achieve.
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