Involvement of Glutathione in the Differentiation of the Slime Mold Physarum polycephalum (cellular differentiation/Physarum/oxy-free radicals/superoxide dismutase/glutathione)

a salts-only starvation medium which induces spherulation. Examination of the cultures at 3-hr intervals indicated that well-defined spherules are not formed until after 21 hr following transfer to differentiation medium. Subsequently, there is a progressive increase in the proportion of cells which have cleaved into spherules. Most of the glutathione in