Production of phenolic-rich extracts from Brazilian plants using supercritical and subcritical fluid extraction: Experimental data and economic evaluation

Abstract Flame vine ( Pyrostegia venusta ) (FV), ice-cream-bean ( Inga edulis ) (IC), dog’s knot ( Heteropterys aphrodisiaca ) (DK), and common bean ( Phaseolus vulgaris L.) (BE) extracts were obtained by supercritical and subcritical fluid extraction (SFE) at 323 K and 35 MPa using pure carbon dioxide (CO 2 ), carbon dioxide with ethanol (CO 2  + EtOH) and carbon dioxide with water (CO 2  + H 2 O). The extraction efficiency was evaluated by factoring in the solvent system and plant matrix influence in extraction yield (EY), antioxidant activity (AA), total phenolic content (TPC) and total flavonoid content (TFC). The manufacturing costs of crude extracts (COM EY ) and phenolic-rich fractions (COM TPC ) were also evaluated. The highest EY was achieved using CO 2  + H 2 O, except for IC extracts. The BE extracts showed the highest TPC (338 mg GAE/g extract, dw), and the highest TFC was obtained for IC extracts using CO 2 (260 mg CE/g extract, dw). AA achieved higher values for FV extracts using CO 2  + EtOH (0.096 mL/mg). The lowest COM EY and COM TPC were obtained for FV and BE extracts using CO 2  + H 2 O in a 0.5 m 3 extraction column.